Start of patient recruitment 09.03.2017
Patients enrolled: 275; Recruiting sites active: 12
"Medical management strategies to prevent recurrent nephrolithiasis are stagnant and stronger evidence is needed to reduce morbidity"
„Given the relatively high prevalence of stones in the general population, there is a puzzling lack of adequate trials.“
"Lower dose thiazide diuretics appear to confer a similar protective effect as higher dose thiazides against the development of kidney stones"
Short summary: In this clinical study, the efficacy of the drug hydrochlorothiazide will be tested in the recurrence prevention of calcium containing kidney stones.
In August 2015, the Swiss National Science Foundation launched the first call to fund Investigator Initiated Clinical Trials (IICT). One of these first round funded IICTs is the NOSTONE trial.
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